It rises in the Gawilgarh hills of eastern Satpura Range in Amravati District of Maharashtra state, and flows southward, draining Amravati, Akola and Buldhana region before emptying into the Purna River in Buldhana District of Maharashtra.
The watershed lies mostly in these three districts of Maharashtra state.
The following villages are located on the banks of Vaan river, Wari Bhairaogad, Warkhed, Sagoda, Danapur, Wadgaon Pr Adgaon, Kolad, Kated, Kakanwada Bk, Kakanwada Kh, Wankhed, Paturda.
The Maharashtra state highways, MH SH 194 cross the river at Wankhed village and MH SH 195 between Kakanwada Bk and Kakanwada Kh village.
There are many places named after the Vaan river.