Khanasir (Arabic: خناصر / ALA-LC: Khanāṣir),[2] also spelt Khanaser, is a town located in Syria's as-Safira District.

[5] A qanat dating back to Byzantine times that served as the water source for the village remained operational well into the 20th century.

According to Robert L. France, Byzantine-era remains of Anasartha "are visible on the street, in newly built walls, and inside residential houses," in Khanasir today.

[11][12] At the turn of the 20th century,[13] Circassian immigrants from Manbij,[14] northeast of Aleppo, settled in Khanasir, using old building materials from the site to reestablish the town.

[6] On 23 February 2016, the Syrian Observatory for Human Rights reported that ISIL had captured the town which is located along a major road and supply route to the city of Aleppo.

Geoffrey Greatrex [de] and Samuel N. C. Lieu write that building work continued in Anasartha in the seventh century and that these epigraphs provide evidence of Roman resistance to Persian invasions.