as-Safira District (Arabic: منطقة السفيرة, romanized: manṭiqat as-Safīrah) is a district of Aleppo Governorate in northern Syria.

Administrative centre is the city of as-Safira.

Since ancient times, as-Safira was a fertile area where grains and other crops were harvested.

The district of as-Safira is divided into five sub-districts or nawāḥī (population as of 2004[1]):

This article about a location in Aleppo Governorate, Syria is a stub.