He is known for his roles as King Ezekiel on the AMC horror drama series The Walking Dead and Dr. Terrell Jackson on the soap opera General Hospital, as well as voicing Cyborg across various DC media and Kaldur'ahm / Aqualad in the animated series Young Justice.

[1] Payton appeared on a recurring basis as Dr. Terrell Jackson on the ABC daytime soap opera General Hospital.

[7] In the cartoon series Justice League, Payton provided the voice of the villain Ten from the Royal Flush Gang.

He also provided the voice of Drebin in the game Metal Gear Solid 4: Guns of the Patriots, Ripcord in G.I.

Joe: Renegades, Blade in Marvel: Ultimate Alliance, Grimlock in Transformers: Robots in Disguise, Quinn Derringer in République and Killer Croc in Batman: Arkham Underworld[8] and voiced Wasabi on the Disney XD original series Big Hero 6: The Series based on the Marvel Comics by Man of Action and the film of the same name.