Khin San Yi (Burmese: ခင်စန်းရီ; also spelt Khin San Yee) is a Burmese development economist, previously served as Minister for Education of Myanmar and Minister for Science and Technology of Myanmar from February 2014 to 30 March 2016.

She became the second Burmese woman to be appointed minister by the Thein Sein administration.

[3][4] In April 2012, she was appointed as a deputy minister at the Ministry of National Planning and Economic Development, where she served under Kan Zaw until his recommendation that she be appointed Minister of Education.

[1] She is an alumna of the Yangon Institute of Economics, graduating with a bachelor's degree in commerce (specialty in accounting and auditing) and a master's degree in trade and marketing.

[5] However, her studies were interrupted when the Burmese government recalled all foreign exchange students in Europe after being subjected by sanctions.