Kholm-Zhirkovsky District (Russian: Холм-Жирковский райо́н) is an administrative[1] and municipal[4] district (raion), one of the twenty-five in Smolensk Oblast, Russia.

It is located in the north of the oblast.

The area of the district is 2,033.40 square kilometers (785.10 sq mi).

[1] Its administrative center is the urban locality (a settlement) of Kholm-Zhirkovsky.

[7] The population of the administrative center accounts for 32.6% of the district's total population.