Dr. Killi Krupa Rani (born 19 November 1965) is an Indian politician from Andhra Pradesh.

[6][7] She entered politics and joined the Indian National Congress party, on the eve of completion of Y. S. Rajashekar Reddy's padhayatra.

She lost the 2004 general election but won in 2009 defeating four-time MP, Yerran Naidu.

[8] In October 2012, she was inducted into the 15th Lok Sabha and Manmohan Singh's cabinet as Minister of State, Communications and Information Technology.

[12] In 2024, she quit the YSRCP citing her dissatisfaction with the leadership and rejoined the INC in the presence of the state unit president Y. S.