[4] Chambers was born in New Zealand and grew up on a sheep farm near Te Kūiti in the King Country in the North Island.
[5] She moved to San Francisco when she was 17 years old to study for a master's degree in science at the University of California, Berkeley.
[7] She began swimming all over the world, including in New Zealand, where she swam the Cook Strait between the North and South Islands.
[5] Chambers supports the efforts of the local pollution watchdog San Francisco Baykeeper, and serves on the organization's Leadership Circle in order to raise awareness about their mission for Bay protection.
[8][9] Chambers is a member of the Explorers Club and she was the first New Zealand woman to be inducted into the International Marathon Swimming Hall of Fame.