[1] Kindling is also referred as an animal visual model of epilepsy that can be produced by focal electrical stimulation in the brain.
[1] With further seizures, the accompanying behavior intensifies, for example progressing from freezing in early stimulations to convulsions in later ones.
[5] The lengthening of duration and intensification of behavioral accompaniment eventually reaches a plateau after repeated stimulation.
[1] However, in both human epilepsy and in some animal models, evidence suggests that a process like that found in kindling does occur.
[6] Here, Delgado and Sevillano demonstrated that repeated low-intensity stimuli to the hippocampus could lead to progressive increase of electrically evoked seizure activity.