Etidlooie began her career as an artist in the late 1950s, when she focused on drawing and carving following the death of her first husband, Elijah.

Between 1970 and 1989, she had more than fifty of her prints published, and she was known as an enthusiastic contributor to the West Baffin Eskimo Cooperatives painting studio following its establishment in 1976.

[2] Her children, Etulu Etidlui, Omalluq Oshutsiaq, Pukaluk Etungat, and Kellypalik Etidlooie, are sculptors.

[1] Stylistically, she is known for well-structured visual works predominantly featuring bird and animal motifs.

As her media of choice evolved from drawings to paintings and prints, her works featured rich, saturated colors and formal composition, as can be seen in her early 1980s prints titled Birds Share A Fish and Lake Trout Near Our Camp.