The Kirksville Osteopaths played as charter members of the Class D level Missouri State League.
[1][2] The 1911 Missouri State League began play in its first season as a five–team league, with the Brookfield Hustlers, Jefferson City Senators, Macon Athletics and Sedalia Cubs teams joining Kirksville as the charter members.
[4] Kirksville was in third place with an 9–12 record under manager Senter Reiney when the franchise permanently folded.
The football team lost a game 150–0 to the Missouri School of Mines on November 12, 1914.
[10][11][12] The name of the home minor league ballpark for the Kirksville Osteopaths is not directly referenced.