Kirkwood is an unincorporated farming town and census-designated place (CDP) in Colerain Township, Lancaster County, Pennsylvania, United States.

It is part of the Lancaster Metro area, in Pennsylvania Dutch Country.

Amish settlers arrived in Kirkwood in 1935 when Isaac and Mary Zook and their nine children moved to the area.

[4] Kirkwood is located at coordinates 39° 50' 50" N 76° 5' 0" W, in southeastern Lancaster County and the center of Colerain Township.

Via Octoraro Creek, the Kirkwood is part of the Susquehanna River water.