It is owned and operated by Central Nippon Expressway Company.

Kii Province (紀伊) consists of the eastern part of present-day Wakayama Prefecture, and Ise Province (伊勢) consists of present-day Mie Prefecture.

[3] The first section of the expressway was opened in 2006 (from the origin to Ōmiya-Ōdai Interchange).

[4] The expressway beyond this point is still in the planning stages and will be built according to the New Direct Control System.

[5] Under this system, the financial burden for planning and building expressways will be shared by both the national and local governments; this differs from the established system which is carried out exclusively by the national government.