Kizema (Russian: Кизема) is a rural locality (a settlement) in Ustyansky District, Arkhangelsk Oblast, Russia, about 700 km northeast of Moscow.

Due to the cold climate, population density here is very small, at only about 2 people per square kilometer.

In September of 1959, the village of Kizema was transferred to the Utsyansky district of the Cherevkovsky oblast.

For a short time, the Russian poet and actor Yuri Vizbor worked as a teacher here after graduation in the 1950s.

The most important economic sectors of Kizema are the lumber industry and railway transport.