On 19 May 2008, Duro completed a transfer to Cypriot outfit Omonia Nicosia, penning a two-year contract until June 2010.
[5] Duro made his competitive debut in the first leg of the first qualifying round versus Milano Kumanovo as the team won 2–0.
[9] Duro continued to impress even further as he was on the score-sheet again on 18 September, where he netted the opener via a free kick against Premier League side Manchester City.
[11] He scored his first career hat-trick on 14 December 2008, netting three times inside 10 minutes in the 4–1 home win against APOP Kinyras.
In August 2010, Duro left Cyprus after two years and joined Austrian Football Bundesliga side LASK on a one-year contract.
Albanian midfielder Klodian Duro was quoted as saying, "Let the world know we're the best here," and after the match fans paraded around with banners that read "This is not Portugal," a reference to the Greeks' stunning win in Euro 2004.
On 24 November 2015, Duro was appointment the new coach of Albanian Superliga side FK Kukësi, replacing Marcello Troisi who was sacked by the club directors due to lack of results.
[24] His first league match in charge was the 2–0 home win versus newly promoted team Kastrioti Krujë.