[3] The county was organized February 14, 1845, and named for U.S. Secretary of War General Henry Knox.

[4] A battle was fought during the American Civil War at Newark, involving Joseph C. Porter on August 1, 1862.

29.30% of all households were made up of individuals, and 16.00% had someone living alone who was 65 years of age or older.

Out of the total population, 24.10% of those under the age of 18 and 16.50% of those 65 and older were living below the poverty line.

The TFR for Knox County in 2004 was relatively high at 2.64, despite the population being 98% white.

[12] The Democratic Party mostly controls politics at the local level in Knox County.