Knoxville Catholic High School, originally located on East Magnolia Avenue, registered 98 young students in 1932.

Additional facilities, including a gymnasium-auditorium, dressing rooms, showers, and a science laboratory, were added to the school.

The decision to move KCHS to a new facility in the Cedar Bluff area in West Knoxville was announced in February 1997.

Chris Michelson, Pastor of St. Albert the Great and Capital Campaign Chair, announced the wing would be dedicated as Schaad Hall.

[citation needed] Faris Field House added 8,000 square feet to the campuses, and includes weight training facilities and athletic offices.

[citation needed] On February 22, 2021, Knoxville Catholic broke ground on the St. Gregory the Great Auditorium.

In 2008, under the direction of head coach Mark Pemberton, the Fighting Irish had a 15–0 season and defeated Memphis Mitchell in the state championship game 28–18.

[3] In 2015, head coach Steve Matthews led the Irish to an 11–4 record and the school's second ever state title after defeating Pearl-Cohn 48–8.