The building was more recently used for adult education programs offered by Knox County Schools.

[1] The building is currently being converted into senior assisted living[2] The Knoxville High School building, located on East Fifth Avenue in Knoxville, was completed in 1910, enrolling male and female students who had previously attended separate high schools.

Enrollment grew to just over 2,000 in the early 1920s and reached a peak of about 2,300 around the beginning of World War II.

[3] By 1948, the building had become inadequate, and city schools Superintendent Tom Prince warned that the Southern Association of Colleges and Secondary Schools was threatening to strip Knoxville High's accreditation.

[1] A World War I monument, erected in 1921, stands on the school's front lawn.