[1][2] Ko's debut acting role was in the 2006 film Do Over, by award-winning director Cheng Yu-chieh.

[3][4][5] She first came to prominence for her role in the domestic hit series Office Girls (2011), in which she played a marketing specialist.

and Someday Or One Day, for which she won the Golden Bell Award for Best Actress in 2016 and 2020 respectively.

[6][7] Beginning 2012, Ko has been in a relationship with actor-singer Hsieh Kun-da, a former member of boy band Energy, whom she had met on the set of the television series Gung Hay Fat Choy.

They held their wedding ceremony at Marriot Hotel Taipei the following year on September 15.