For his doctoral work, he addressed how temporal gene expression and antibody specificities contribute toward the repertoire of B lymphocytes in various lymphoid organs in mice.
Dr. Ravichandran then moved to at Dana–Farber Cancer Institute[1] (Boston, MA) to pursue his post-doctoral research under the guidance of Dr. Steven Burakoff.
Here, he focused on intracellular signaling in T cells, and addressed the role of adapter proteins (particularly Shc), and published multiple high impact publications (1992-1996).
[2] In 1996, Dr. Ravichandran moved to the University of Virginia School of Medicine (Charlottesville, VA) as Assistant Professor to establish his independent laboratory.
Failure to promptly and efficiently clear apoptotic cells can lead to an aberrant immune response, promoting chronic inflammation and autoimmunity.
Twelve former postdoctoral fellows currently hold faculty positions in different countries, including United States, Australia, Switzerland, Korea, and Japan.