Konoe Motozane (近衛 基実, 1143 – August 23, 1166) was a Japanese statesman, regent and kugyō during the late Heian period.

Motozane was born in 1143, to his father Fujiwara no Tadamichi.

Motozane married the daughter of Fujiwara no Tadataka, whom he later divorced, and remarried to Taira no Moriko, the fourth daughter of Taira no Kiyomori.

At the age of 16 he assumed the position of kampaku, regent, to Emperor Nijō, becoming the head of the Fujiwara clan.

He died at the age of 24, a year after he became sesshō, or regent, to Emperor Rokujō, leaving his wife Taira no Moriko windowed at the age of 12.