He served as the Minister of Rural Development & Panchayati Raj, Law & Parliamentary Affairs from 2018 to 2019 in the cabinet of H D Kumaraswamy.
His father C. Byre Gowda was a senior legislator and Cabinet Minister of Karnataka State, having served as an M.L.A.
He began his political career in 2003, when his father and All India Progressive Janata Dal leader, C. Byre Gowda passed away.
[3] In October 2003, Krishna Byre Gowda contested and won the by-election to fill his late father's legislative assembly seat from Vemgal, Kolar District, to become one of the youngest members of the Karnataka legislature.
[4] In April 2004, Krishna Byre Gowda left the All India Progressive Janata Dal political party to join the Indian National Congress and won from Vemgal, Karnataka legislative assembly seat.
[5] Krishna Byre Gowda became president of the Karnataka Pradesh Youth Congress Committee in November 2007.
He has also taken up various initiatives like the construction of auditoriums, toilets, dining halls and additional classrooms in Byatarayanapura government schools with C.S.R assistance from R.V Trust.
He also introduced Krushi Bhagya to provide farmers with farm ponds locally known as "Krishi Hondas" not only to protect crops during severe droughts but also to ensure a good yield.