[3][4] Shenoy was the Hong Seh and Vivian W. M. Lim Professor in the Stanford University School of Engineering.

[14][15] Shenoy and his team made fundamental discoveries about how the brain encodes and executes motor commands, applying those insights to improving brain-computer interfaces.

To this end, they developed a mathematical framework for analyzing neural activity called 'computation through dynamics'.

[16] In 2022 Shenoy was elected member of the National Academy of Medicine "For making seminal contributions both to basic neuroscience and to translational and clinical research.

His work has shown how networks of motor cortical neurons operate as dynamical systems, and he has developed new technologies to provide new means of restoring movement and communication to people with paralysis.