Kulsoom was born on 29 March 1948[2][3][4] in Lahore into the Punjabi Kashmiri family, to Mohammed Hafiz Butt.

[13] His second term as prime minister was ended when then Chief of Army Staff General Pervez Musharraf led a military coup d'état against him on 12 October 1999.

[14] Kulsoom was arrested by the Pakistan Army Corps of Military Police and immediately shifted to her local residence.

[6] According to her daughter, Maryam Nawaz, Kulsoom "dauntlessly challenged the usurper when a lot of men backed out".

[16] Kulsoom was elected to the National Assembly of Pakistan for the first time from NA-120 (Lahore-III) as a candidate of PML (N) in by-polls held in September 2017.

The NA-120 seat fell vacant after her husband, Nawaz Sharif, was disqualified by the Supreme Court of Pakistan in the Panama Papers case.

[25] On 14 September 2018, in Lahore, a funeral prayer led by Maulana Tariq Jameel was offered at Sharif Medical City around 5:30 pm PKT before she was laid to rest in Jati Umra.