[citation needed] Gyimah-Brempong has taught at the New College of Florida from 1981 to 1988, and at Wright State University from 1988 to 1994.
Since 1994, he has been a professor of economics at the University of South Florida.
[citation needed] From 2002 to 2004 he was the Economics Program, Director for the National Science Foundation.
[1] His research focuses on economic development in Africa.
[2] In 2016, the Association for the Advancement of African Women Economists held a conference in his honor.