The Kwelera National Botanical Garden is located at the Kwelera Nature Reserve on the Wild Coast of the Eastern Cape.

[1] In 1994, the 6.96 ha (17.2 acres) Kwelera Island Local Nature Reserve was established as a protected area at the mouth of the Kwelera River.

[2] In 2014, 10.48 ha of farmland beside the Kwelera Nature Reserve was purchased by SANBI for the creation of the Kwelera National Botanical Garden.

It would be jointly managed by SANBI and Eastern Cape Parks.

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