The Kwilu River (Portuguese: Rio Cuílo; French: Rivière Kwilu; Dutch: Kwilu Rivier) is a major river in both Lunda Norte Province and Lunda Sul Province in Angola as well as Kwilu Province, formerly known as Bandundu province, in the Democratic Republic of the Congo (DRC) to the city of Bandundu, where it joins the Kwango River just before this stream enters the Kasai River.

In the DRC the river flows past the towns of Gungu, Kikwit, Bulungu, Bagata, Rutherfordia and Bandundu.

[1] Lusanga, formerly Leverville, lies at the location where the Kwenge River joins the Kwilu, between Kikwit and Bulungu.

In the wet season the flooded area covers 1,550 square kilometres (600 sq mi).

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