His poetry, essays, translations, and critical analysis celebrate the ideas of Western civilisation, expressed through the language and history of Greek culture.

His poetic opus adds to the tradition established by such modern Greek poets as Constantine P. Cavafy, Giorgos Seferis and Odysseas Elytis.

His poetry though holds steadfastly to the Greek Cypriot linguistic register.

In 2007, he was awarded the Literary, Arts and Sciences Prize of the Republic of Cyprus.

Charalambides's work has been translated in many languages in various monographs: Moreover, his work has been set to music by Chrysostomos Stamoulis, Notis Mavroudes, Michalis Christodoulides, Marios Tokas, Savvas Savva, Marios Meletiou and George Kalogyrou.