A native of Quivicán, Cuba, Medina made his Negro leagues debut in 1944 with the Cincinnati-Indianapolis Clowns, and played with the club again in 1945.
He went on to play for Alijadores de Tampico of the Mexican League in 1946 and 1947; in the latter, Medina also appeared in games for Tuneros de San Luis and Diablos Rojos del Mexico, who also competed in the Mexican League.
Medina's last season in the Mexican League was 1948, in which he played with Diablos Rojos del Mexico.
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