LaGrange is a town in Lee County, Arkansas, United States.

LaGrange is located in southern Lee County at the western foot of Crowley's Ridge.

According to the United States Census Bureau, LaGrange has a total area of 0.15 square miles (0.39 km2), all land.

The racial makeup of the town was 43.44% White and 56.56% Black or African American.

There were 9.5% of families and 7.6% of the population living below the poverty line, including no under eighteens and 11.3% of those over 64.