By 1541 the Spanish conquistadors arrived in the town, led by Álvaro de Mendoza, deputy to Marshal Jorge Robledo.

On arrival to this region, Mendoza discovered a vast and fertile valley full of green meadows furrowed by abundant and clean water.

[2] It was founded by María Josefa Marulanda Londoño and Father José Pablo de Villa.

The main agricultural products of the Municipality are tamarillo, bananas, blackberries, caturro and coffee, and other fruits and vegetables.

To the north of the city, there are many cut flower growers and exporters, which provide the main source of employment for La Ceja's inhabitants.

The former chapel is also considered a museum of religious art, and contains works by artists such as Gregorio Vasquez de Arce y Ceballos.