Through his on-screen romantic (and later marital) relationship with her, Edge became part of the family and the group largely revolved around protecting his interests although they would often help out other members as well.

While the group consisted of six members, Vickie and Edge were the central focus and were known for their grotesquely hyperbolised displays of affection, such as primal kisses.

[1] As well as frequently kissing on screen, the couple often showed video packages of them in comically blissful situations such as playing on swings and feeding each other while having a picnic.

Edge was noted for his ability to indulge in comically entertaining scenes without losing his potency as a convincingly detestable character.

[2] The seeds for what became La Familia began to take hold when Edge returned to WWE in November 2007 after recovering from a four month injury which had forced him to vacate the World Heavyweight Championship.

[5] He returned at the Survivor Series pay-per-view on November 18, posing as a camera man to enter a Hell in a Cell match and cost The Undertaker his World Heavyweight Championship against then-champion Batista.

Vickie, begrudgingly being pushed to the ring by Long, brought with her the World Heavyweight Championship and then introduced Edge to present the title to him.

[24] Later that month, on the May 16 episode of SmackDown, Vickie was forced by the WWE Board of Directors to compete against The Undertaker in what she subsequently made a six-on-one handicap match featuring all of La Familia.

[27] The next month at One Night Stand on June 1, a rematch for the vacant championship was given two stipulations: firstly it was a Tables, Ladders, and Chairs match, Edge's specialty; and secondly, if The Undertaker lost, he would be banished from WWE.

After interference from La Familia, Edge reclaimed the World Heavyweight Championship after pushing The Undertaker off a ladder and through four tables, forcing his storyline exile from WWE television.

[28] Following this, Batista set his sights on Edge and avoided being banished himself by beating The Great Khali to earn a title match.

[31] On the July 4 episode of SmackDown, Edge's frustrations about losing the World Heavyweight Championship which he could not reclaim materialized when he assaulted Festus, an opponent of Hawkins and Ryder, and canceled his wedding with Vickie.

However, also during the evening The Hardys were forced to compete against each other, but tipped over the wedding cake in protest and the show ended with Triple H giving a mock celebration speech.

[37][38] On the August 15 episode of SmackDown, a week after having already turned on the others, Edge kidnapped Vickie in her wheelchair and rode her round the building taunting her until he pushed her to the ring, tipping her out onto the stage and then lying next to her, watching a montage video of their moments together mixed with advice received from Mick Foley about having to become more tough and deranged (like his old self) to defeat The Undertaker.

[43] At Unforgiven on September 7, Big Show came to the ring to voice his frustration at Vickie for keeping him out of the main event match.

[44] Big Show was revealed to be protecting Vickie in a strictly business arrangement, though he would unwittingly leave her at the hands of The Undertaker on the September 26 episode of SmackDown, resulting in her receiving another Tombstone Piledriver[45] which put her back in a wheelchair.

However, at the same event, SmackDown's WWE Championship match was missing a competitor after Jeff Hardy was reported to have been hospitalised after being attacked in his hotel as part of the storyline.

Hardy chased out afterwards in a neck brace swinging a chair, but accidentally hit Triple H and Kozlov, allowing Edge to gain an easy pin to win the WWE Championship.

[51] As both world champions were forced to defend their championships inside an Elimination Chamber, Edge opened No Way Out on February 15 by being the first competitor in the ring, opposite Jeff Hardy.

This ensured Edge had lost the WWE Championship and a new champion would be crowned, ultimately Triple H. Living up to his nickname of the Ultimate Opportunist, though, Edge later appeared in the main event of the evening by attacking Kofi Kingston with a chair until he was unable to compete in the Elimination Chamber for the World Heavyweight Championship, locking himself in one of the pods and refusing to come out.

[52] The following night on Raw, Vickie explained that with Raw General Manager Stephanie McMahon absent tending to her brother Shane in the hospital after his match with Randy Orton, she was the highest in command and with Kingston injured a replacement had to be found, giving Edge's forced entry into the match carte blanche.

[55] Edge revealed that he had asked Big Show to look after Vickie while he was gone[54] and consequently gave him a World Heavyweight Championship match at WrestleMania 25 on April 5.

She also booked Edge in a rematch for the World Heavyweight Championship against John Cena at Backlash on April 26 and made it a Last Man Standing match.