La Mata de Ledesma is a village and municipality in the province of Salamanca, western Spain, part of the autonomous community of Castile-Leon.

It is located 30 kilometres (19 mi) from the provincial capital city of Salamanca and has a population of 110 people.

The municipality covers an area of 38.55 km2 (14.88 sq mi).

It lies 814 metres (2,671 ft) above sea level.

This article about a location in the province of Salamanca, Spain, is a stub.