[1] Located in the southeastern region of the province, it is bordered within Manitoba by the neighbouring electoral divisions of Lac du Bonnet, Dawson Trail, Steinbach, Springfield-Ritchot, Midland, and Borderland to the west and north;[2][3] by the province of Ontario to the east; and by the U.S. state of Minnesota to most of the south.

[1] Communities in the riding include Buffalo Point (and Buffalo Point First Nation), Gardenton, Grunthal, Kleefeld, La Broquerie, Marchand, Middlebro, New Bothwell, Otterburne, Piney, St. Malo, St-Pierre-Jolys, Sarto, Sprague, Stuartburn, Sundown, Vassar, Vita, and Woodridge.

[4][2] La Vérendrye was a hotly contested riding between the Liberals and Conservatives in its earliest years.

The La Vérendrye riding has remained under PCs since 2011, with Konrad Narth most recently being elected in October 2023 to replace retiring MLA Smook.

[3] The construction industry accounts for 15.2% of the riding's labour force, followed by agriculture, forestry, fishing, and hunting at 14%.