Guadiana is a Spanish limited crime mystery television series created by Agustín Martínez.

Set in a sleepy Andalusian village near the Portuguese border, it is a follow-up to La caza.

Twelve years after a massacre in the riverside village of Frontera de Guadiana (located in the Spanish-Portuguese border) by teen Mario (whose criminal case was handled by a young Sara Campos and lieutenant Baín), sergeants Selva and Gamero investigate the disappearance of a woman, Alicia, in the village.

[1][2] The series was produced by RTVE in collaboration with DLO Producciones.

Shooting locations in the province of Huelva included Sanlúcar de Guadiana, Ayamonte, Isla Cristina, Lepe, and El Granado.