"La differenza tra me e te" (Italian: [la diffeˈrɛntsa tra mˈme e tˈte]) is a pop song written by Italian pop singer Tiziano Ferro.

It was released as the first single from his fifth album L'amore è una cosa semplice (2011) and achieved success in Italy, where it was certified double platinum by the Federation of the Italian Music Industry,[1] and in Belgium.

A Spanish-language version of the song was also released.

Titled "La diferencia entre tú y yo", it served as the first single from El amor es una cosa simple, the Spanish edition of Ferro's fifth studio album.