1I0Z, 1T2F394516832ENSG00000111716ENSMUSG00000030246P07195P16125NM_001174097NM_002300NM_001315537NM_008492NM_001302765NM_001316322NP_001167568NP_001302466NP_002291NP_001289694NP_001303251NP_032518Lactate dehydrogenase B is a protein that in humans is encoded by the LDHB gene.

[5] This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process.

Alternatively spliced transcript variants have been found for this gene.

Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes.

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