Renfroe pitched with a sidearm delivery and appeared primarily as a relief pitcher and closer throughout his nine-year professional career.

Renfroe walked on to the baseball team at the University of Mississippi, where he set school records for the most career pitching appearances[1] and wins.

He was called up to the Chicago Cubs on July 2, 1991,[4][5] and made his Major League debut the following day at Wrigley Field against the Pittsburgh Pirates.

[7] The resultant head trauma caused him speech and vision problems,[4] and he retired thereafter, in part because of sustained complications from the injury.

[4] Renfroe was born in Natchez, Mississippi but moved to Nashua, New Hampshire with his family at a young age.