Lafayette Leake (June 1, 1919 – August 14, 1990) was an American blues and jazz pianist, organist, vocalist and composer who played for Chess Records as a session musician, and as a member of the Big Three Trio, during the formative years of Chicago blues.

[6] During the 1960s, Willie Dixon formed the Chicago Blues All-Stars, with Leake as resident pianist.

Leake's song "Wrinkles", performed by the Big Three Trio, was featured on the soundtrack of David Lynch's 1990 film, Wild at Heart.

[9] Leake fell into a diabetic coma in his home in Chicago, where he remained undiscovered for several days, dying in hospital on August 14, 1990.

[3] With Chuck Berry With Bo Diddley With John Lee Hooker With Howlin' Wolf With Magic Sam With Sonny Boy Williamson