[7] In its native range (in the Red Sea) the silver-cheeked toadfish lives on rocky bottoms from shallow coastal waters down to a 250 m depth (820 ft).

In December 2018, A Semana, a Cape Verde Islands paper published that this fish was caught in its waters, off West Africa.

[8] The silver-cheeked toadfish is very similar to the oceanic pufferfish but more elongated and with a symmetrical caudal (tail) fin.

Similar to other puffer fishes, the silver-cheeked toadfish is extremely poisonous if eaten because it contains tetrodotoxin in its ovaries and to a lesser extent its skin, muscles and liver, which protects it from voracious predators.

[9] This deadly substance causes paralysis of involuntary muscles, which may cause its victims to stop breathing or induce heart failure.