U.S. News & World Report has cited it several times on its list of "America's Best Hospitals" in the category of urology.

Faced with an expanding patient base (notable patients included former United States president John F. Kennedy),[5] discussions for a new facility were drafted in partnership with New England Baptist Hospital, which long held close ties to Lahey Clinic.

A transition to its current facility in Burlington, Massachusetts was completed in November 1980 under the leadership of then CEO, Dr. Robert E Wise.

The combined system was Massachusetts largest network of hospitals and doctors with a market share of 22% in the eastern part of the state.

In December 2017, a group called the Make Healthcare Affordable Coalition came out in opposition to the proposed merger of Lahey Health and Beth Israel Deaconess Medical Center citing the "mega merger" would lead to higher costs and the closing of health clinics serving minority communities.