[1] Invertebrates, turtles and the aquatic frog Xenopus tropicalis are common in the lake,[1][2] which is also an important sanctuary for birds.

[3] Seven fish species are known from the lake, including Enteromius callipterus and a Clarias catfish, while the remaining all are cichlids: Coptodon kottae, Chromidotilapia guentheri, Hemichromis fasciatus, Pelmatolapia mariae and Sarotherodon galilaeus.

A review in 2008 was unable to confirm the distinction of the subspecies loennbergi compared to C. guentheri elsewhere, but the H. fasciatus in Barombi Koto and Lake Mboandong are unusually small and might be an endemic undescribed species.

[1] Bulinus snails (including the near-endemic B. camerunensis) infested with Schistosoma, which causes the disease bilharzia in humans, are present in the lake.

[1] Lake Mboandong is less rich in phytoplankton and has less fish species, but all are species shared with Lake Barombi Koto and its inflowing streams: Aphyosemion bivittatum, Fundulopanchax oeseri, Coptodon kottae, Hemichromis fasciatus and Sarotherodon galilaeus.