Lake Cormorant is an unincorporated community located in DeSoto County, Mississippi, United States.

Klack's General Store in Lake Cormorant is where blues singer Son House was recorded for the Library of Congress in 1941.

Just to the east of the community is the Lake Cormorant site of a former Mississippian culture Quizquiz village, which is likely one visited by Hernando de Soto in 1542.

[4] Levees and floodways built under the federal Flood Control Act of 1928 divert water away from the hamlet, and into the Lake Cormorant Bayou.

[5][6] The climate in this area is characterized by hot, humid summers and generally mild to cool winters.