(Koyukon: Menchuh Mene’ [mənt͡ʃʰuh mənə]; Upper Kuskokwim: Minchu Mina’) is a census-designated place (CDP) in Yukon-Koyukuk Census Area, Alaska, United States.

Minchumina has a continental subarctic climate (Köppen Dfc).

Lake Minchumina first appeared as an unincorporated village on the 1950 U.S. Census.

The racial makeup of the CDP was 84.38% White, 3.12% Native American, and 12.50% from two or more races.

37.5% of all households were made up of individuals, and 6.3% had someone living alone who was 65 years of age or older.