The Sesto Elemento is equipped with Lamborghini's 6-speed "e-gear" automated manual transmission and an all-wheel-drive system, mated to a 5.2 litre V10 engine borrowed from the Gallardo Superleggera, generating 570 PS (419 kW; 562 hp) and 540 N⋅m (398 lbf⋅ft) of torque.

[citation needed] The interior of the Sesto Elemento is generally bare without vehicle comforts such as air-conditioning and stereo.

The Sesto Elemento also lacks seats, instead having foam padding directly adhered to the carbon fibre chassis.

[2][6] At that time, the Sesto Elemento was the most expensive Lamborghini ever made, until the Veneno was launched, with the price of the car as high as GB£4,162,150 (US$6.5 million).

[citation needed] Due to lack of interest for such an expensive car that was not road legal, Lamborghini was unable to find 20 customers willing to purchase the Sesto Elemento.