Additional highlights include: Brewster turned professional in 1996 and was undefeated for his first three years as a pro until losing decisions to Clifford Etienne and Charles Shufford in 2000.

In the fifth round, Brewster hurt Klitschko with a left hook that forced the Ukrainian fighter to use the ropes to hold himself up, which resulted in a knockdown.

Seeing Klitschko struggle to return to his feet, referee Robert Byrd stopped the fight and awarded a technical knockout victory to Brewster.

[2] Brewster lost his WBO title by unanimous decision on April 1, 2006 to Sergei Liakhovich from Belarus in an action-packed fight.

Lamon Brewster returned to the ring on July 7, 2007, losing his rematch against Wladimir Klitschko after trainer Buddy McGirt stopped the fight after the sixth round.

At one point in his career, Brewster was managed by The Simpsons co-creator, professional poker player and philanthropist, Sam Simon,.

Brewster founded "Fighting Connection Consulting" in July 2011 providing expertise to professional fighters on training methods, psychology, nutrition, conditioning, team building, and publicity.