Wladimir Klitschko vs. Lamon Brewster was a professional boxing match contested on April 10 2004, at the Mandalay Bay Resort & Casino in Las Vegas, Nevada, for the WBO Heavyweight Championship.

Following these fights Roach left the Klitschko camp to make way for new lead trainer Emanuel Steward who had become available after the retirement of WBC & Lineal champion Lennox Lewis.

Brewster was on a five-fight win streak (all by TKO) since his 2000 defeats against Clifford Etienne & Charles Shufford, he was previously set to challenge newly crowned WBO title holder Corrie Sanders, who declined the fight in favour of a bout with Vitali Klitschko for the vacant WBC belt.

[5] After a press conference before the fight Brewster was seen in tears after talking about Slayton's death, in sullen anger punching the microphone off its mount and on to the floor, leading to comparisons with Buster Douglas whose mother passed away in the build-up to his title bout with Mike Tyson.

Before the start of the final round Spinks' trainer Kevin Cunningham told the champion to "Don't get reckless", believing that they led clearly on the cards.

After making it back to his feet Klitschko attempted to return to his corner but Byrd waved the fight off, giving Brewster a TKO victory and the WBO belt.

[15] On 12 April, he arrived in Las Vegas and provided blood and urine samples for an independent examination, which was supposed to be done by Donald Katlin, who specialized in such cases.

The drug has no taste or smell and causes mental disorders, which are accompanied by impaired coordination, a weakening reaction and overall physical weakness.

[19] Judd Bernstein, the lawyer representing Klitschko, suggested that he was a victim of an ongoing fight fixing in Las Vegas (which also included fraudulent medical reports), which was investigated by FBI at the time.

[20] Bernstein, along with some other journalists, pointed out that in the last 48 hours before the beginning of the fight, the betting odds in favor of Klitschko rapidly dropped from 11-to-1 to 3.5-to-1.

The two boxers fought a rematch in 2007 with Brewster's corner asking the fight to be stopped at the end of the sixth round, and throughout the rest of his long career Klitschko used this loss as a driving force, saying in an interview with ESPN's Dan Rafael: "I will be thankful to Lamon until my grave.