He has played the roles of Winston Bishop in the Fox sitcom New Girl (2011–2018), Daniel in Call Me Kat, Darrin Morris in the National Geographic docudrama Valley of the Boom (2019), about the 90s tech boom, cartoonist Keef Knight in the Hulu comedy Woke (2020–2022),[2] and North Dakota State Trooper Whitley "Witt" Farr in the fifth season of Fargo, for which he won a Primetime Emmy Award.

[7] Morris appeared in commercials for State Farm Insurance, Taco Bell, Twix, Miller Lite, Las Vegas, 7 Up, Edge, Sears, Microsoft Windows, Chili's, McDonald's, Ford, and Hornitos Tequila.

[12][5] In November 2018 it was announced that Morris would be starring in a half-hour sitcom, Woke, based on cartoonist Keith Knight's autobiographical comic strip The K Chronicles on Hulu.

[14] Morris has also appeared in the films Barbershop: The Next Cut (2016), Game Night (2018), The Christmas Chronicles (2018), Jumanji: The Next Level (2019), Yesterday (2019), Bloodshot (2020), and Desperados (2020).

[15] In April 2021, it was announced that Morris would co-star in an Indie horror film titled Night Shift, alongside Phoebe Tonkin and Madison Hu.

[17] In 2022, he was cast as North Dakota State Trooper Whitley "Witt" Farr in the fifth season of the FX black comedy-crime drama anthology series Fargo, which premiered in November 2023 and concluded in January 2024.

[18] In July 2024, it was announced Morris was set to play Robbie Robertson in the upcoming Spider-Noir television show on Amazon Prime Video.