It is part of the Lancaster Independent School District and serves students in grades nine through twelve.

[4] As the district grew, a new high school located on Centre Avenue (site of the LISD current administration building) opened in 1923.

[4] Spurred by rapid population in both the city and school district, Lancaster voters approved a $110 million bond package in February 2004 - $65.3 million of which was dedicated to the construction of a new high school complex with athletic facilities, a stadium, and an auditorium.

[5] The site chosen for the complex was a plot of land located immediately north of the 170 acre[6] Lancaster Community Park.

[9] 61.5% of the Lancaster High School student body was considered Economically Disadvantaged with 60.0% classified as "At-Risk.

Holly K. Hacker of The Dallas Morning News said that Lancaster High may have been affected by institutional issues in LISD.

Tigers football team faced Cedar Park in the state championship game losing 7-17 due to 10 unanswered points in the 4th Quarter.