Guidry served as defensive backs coach for Miami during its 2010 MAC championship season.

That season Miami orchestrated the second largest turnaround in the history of college football going 10–4 after winning just one game (1–11) the year before.

Guidry served as interim head coach for Go-Daddy.com Bowl, leading the Redhawks to a 35–21 victory over Middle Tennessee.

Head Coach Willie Taggart left prior to the Little Caesar's Bowl, and once again Guidry was tabbed as the Interim Head Coach for the bowl game, where the Hilltoppers lost a tight game to Central Michigan in the waning minutes of the 4th quarter (24–21).

[6] In January 2021, it was announced that Guidry would be joining Charles Huff's inaugural staff at Marshall University as the Thundering Herd's defensive coordinator.

On January 20, 2023, it was announced that Guidry was hired as the defensive coordinator for the 2023 Tulane Green Wave football team, replacing the outgoing Chris Hampton.

Despite the improved record, much of the success in 2024 was attributed to Heisman runner-up quarterback Cam Ward, whose stellar play carried the team.